Colivelin PureRawz

PureRawz Colivelin Hybrid Neuroprotective Research Peptide

PureRawz Colivelin is a high-purity synthetic hybrid peptide developed for advanced biochemical and neuroscience research applications. It is engineered by combining an activity-dependent neurotrophic factor (ADNF) fragment with a humanin analogue, creating a structurally complex peptide used in experimental studies of neuronal signaling and cellular survival pathways.

At nexacore.pk, we provide premium-grade research peptides and biochemical compounds across Pakistan, offering consistent, laboratory-quality materials intended strictly for scientific and experimental use.

What is Colivelin?

Colivelin is an investigational hybrid peptide designed for research into neurobiological signaling mechanisms. It is commonly used in in vitro and preclinical models to study how peptide structures influence neuronal survival, intracellular communication, and stress-response pathways.

Due to its synthetic fusion design, Colivelin is widely utilized as a model compound in neuroscience and peptide biology research.

Key Features

• High-purity synthetic hybrid peptide
• Molecular Formula: C₁₁₉H₂₀₆N₃₂O₃₅
• Molecular Weight: 2645.1 g/mol
• CAS Number: 867021-83-8
• PubChem CID: 90477169
• Lyophilized peptide stored at -20°C or below
• Soluble in water and DMSO (research-grade solvents)
• Research Use Only (RUO) compound

Mechanism of Action (Research Overview)

In experimental research models, Colivelin is studied for its involvement in multiple intracellular signaling pathways related to neuronal survival and cellular stress response.

STAT3 Signaling Pathway

Colivelin has been observed in research settings to influence STAT3 (signal transducer and activator of transcription 3) signaling. This pathway is associated with gene regulation linked to cell survival and anti-apoptotic responses.

Ca²⁺/Calmodulin-Dependent Kinase Pathway

Research also suggests involvement of calcium-dependent signaling mechanisms, including CaMKIV activation, which plays a role in neuronal response and intracellular communication.

These pathways are analyzed in controlled laboratory systems to better understand peptide-mediated neurobiological signaling.

Research Applications

PureRawz Colivelin is commonly used in:

• Neuroprotective pathway research
• Neuronal stress response studies
• STAT3 signaling investigations
• Calcium-dependent kinase pathway analysis
• Hybrid peptide structural studies
• Cell survival and apoptosis research models
• Neuroscience and biochemical signaling experiments

Scientific Importance

Colivelin serves as a valuable research model for studying hybrid peptide behavior and its effects on intracellular signaling networks. Its structural complexity makes it useful for understanding how peptide fusion molecules interact with neuronal pathways in experimental systems.

Why Choose PureRawz Colivelin?

• High-purity hybrid peptide research compound
• Reliable quality for advanced neuroscience studies
• Well-characterized experimental peptide model
• Suitable for in vitro and preclinical research
• Available in Pakistan via nexacore.pk

Storage Information

• Store lyophilized peptide at -20°C or colder
• Protect from moisture and repeated freeze-thaw cycles
• Use appropriate laboratory handling procedures
• Keep container tightly sealed

Important Disclaimer

PureRawz Colivelin is intended strictly for laboratory and research purposes only. It is not approved for human consumption, veterinary use, or medical treatment. All research must be conducted under appropriate institutional and regulatory guidelines.