N-Acetyl Epithalon Amidate PureRawz
N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) Overview
N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is a research-grade synthetic tetrapeptide. It is derived from the parent compound Epithalon (Epitalon), originally characterized from the bovine pineal gland. It's an investigational compound and is not approved for clinical use. It is supplied exclusively for controlled laboratory and in vitro research applications. The compound has a four-amino-acid sequence Alanine-Glutamic acid-Aspartic acid-Glycine (AEDG) of the parent peptide. In addition, it has two deliberate structural modifications that researchers believe significantly enhance its physicochemical profile for research settings.
| Product Code | VDF-66 |
| Availability | In Stock |
| Type | Spray |
| Category | N-Acetyl Epithalon Amidate |
| Brand | PureRawz |
| Shipping | 01 day shipping. (Free pickup today) |
PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2)
PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is a high-quality synthetic tetrapeptide developed for advanced laboratory research. Derived from the parent peptide Epithalon (Epitalon), this modified compound incorporates structural enhancements designed to improve molecular stability and resistance to enzymatic degradation.
Its peptide sequence consists of Alanine, Glutamic Acid, Aspartic Acid, and Glycine (AEDG), while N-terminal acetylation and C-terminal amidation provide greater physicochemical stability, making it highly suitable for controlled research environments.
Researchers commonly investigate this compound in studies involving cellular aging pathways, telomere biology, oxidative stress, peptide engineering, and circadian rhythm signaling.
Key Features
- Premium-quality research peptide from PureRawz.
- Modified Epithalon analog with enhanced stability.
- N-terminal acetylation and C-terminal amidation.
- High purity of ≥98% verified through HPLC analysis.
- Suitable for molecular and biochemical research.
- Commonly studied in telomere and longevity-related pathways.
- Certificate of Analysis available for quality verification.
- Manufactured to strict research-grade standards.
Structural Modifications for Enhanced Stability
N-Terminal Acetylation
The addition of an acetyl group at the N-terminus helps increase peptide stability by reducing susceptibility to aminopeptidase degradation. This modification contributes to improved consistency and performance during laboratory analysis.
C-Terminal Amidation
C-terminal amidation converts the terminal carboxyl group into an amide group, enhancing resistance to enzymatic breakdown and supporting peptide integrity during experimental studies.
Together, these modifications provide superior stability compared to the parent Epithalon peptide.
Proposed Mechanism of Action
Epigenetic Research
N-Acetyl Epithalon Amidate is being investigated for its interactions with chromatin-associated structures and gene transcription pathways. Preclinical models have explored its role in regulating molecular signaling and cellular processes.
Telomere and Telomerase Studies
Researchers have studied this peptide for its involvement in telomerase-associated pathways and telomere maintenance mechanisms. These investigations contribute to understanding cellular longevity and proliferative capacity under laboratory conditions.
Oxidative Stress Research
Experimental models have evaluated the compound's effects on oxidative stress markers and endogenous antioxidant signaling pathways, providing insight into cellular defense mechanisms.
Circadian Rhythm Investigations
The peptide has attracted scientific interest in studies involving pineal gland signaling, clock gene expression, and molecular mechanisms associated with circadian rhythm regulation.
Potential Research Applications
Cellular Aging and Longevity Research
Epithalon analogs are commonly investigated in studies involving:
- Cellular senescence pathways.
- Telomere biology.
- Gene expression mechanisms.
- Molecular longevity research.
Circadian Rhythm and Pineal Signaling
Researchers utilize this peptide in controlled studies examining:
- Melatonin-associated pathways.
- Pineal gland peptide interactions.
- Circadian signaling mechanisms.
Oxidative Stress and DNA Stability
The compound is also used in investigations related to:
- Oxidative stress biomarkers.
- Genomic stability.
- Cellular protection pathways.
Peptide Engineering
Due to its modified structure, N-Acetyl Epithalon Amidate is frequently studied for:
- Proteolytic resistance.
- Peptide stability.
- Structure-function relationships.
- Molecular delivery characteristics.
Biochemical and Receptor Studies
Researchers incorporate this peptide into:
- Receptor-binding experiments.
- Peptide characterization workflows.
- Cellular pathway investigations.
- Molecular pharmacology research.
Why Choose PureRawz N-Acetyl Epithalon Amidate?
PureRawz is recognized worldwide for producing premium-quality research compounds with exceptional purity and consistency. Every batch undergoes rigorous quality control and third-party verification to ensure researchers receive reliable materials for advanced scientific studies.
Benefits include:
- ≥98% purity verified by HPLC.
- Batch-specific Certificate of Analysis.
- Enhanced peptide stability.
- Strict quality standards.
- Reliable manufacturing consistency.
- Trusted by research professionals.
At nexacore.pk, customers throughout Pakistan can access premium peptides, SARMs, nootropics, and performance-enhancement research compounds from trusted international brands. We are committed to providing authentic products, competitive pricing, and dependable service to researchers seeking top-quality research materials.
Product Specifications
| Specification | Details |
|---|---|
| Compound Name | N-Acetyl Epithalon Amidate |
| Alternative Name | Ac-AEDG-NH2 |
| Peptide Sequence | Ala-Glu-Asp-Gly |
| Molecular Formula | C14H22N4O9 |
| Molecular Weight | 390.35 g/mol |
| CAS Number | 307297-39-8 |
| Classification | Synthetic Tetrapeptide |
| Structural Modifications | N-Terminal Acetylation and C-Terminal Amidation |
| Purity | ≥98% |
| Storage Conditions | -20°C, Protected from Light and Moisture |
| Brand | PureRawz |
Handling and Storage
For optimal stability, N-Acetyl Epithalon Amidate should be stored at -20°C and protected from moisture, heat, and light exposure. Avoid repeated freeze-thaw cycles and handle using appropriate laboratory safety procedures, including gloves, protective clothing, and eye protection.
Disclaimer
PureRawz N-Acetyl Epithalon Amidate (Ac-AEDG-NH2) is intended strictly for laboratory and research purposes only. This product is not approved for human consumption, veterinary use, or therapeutic applications. The information provided is for educational purposes and should not be interpreted as medical advice or treatment recommendations.
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