Pregnanolone Neurosteroid – PureRawz

Pregnanolone is a naturally occurring neuroactive steroid produced as part of progesterone metabolism within steroidogenic pathways. It belongs to a class of endogenous neurosteroids that play a key role in regulating neurotransmission and neuroendocrine signaling in experimental research models.

Available in Pakistan through nexacore.pk, this high-purity Pregnanolone research compound by PureRawz is intended exclusively for laboratory and scientific studies involving neurosteroid biology, receptor signaling, and GABAergic system research.

Key Features

• High-purity Pregnanolone neurosteroid compound
• Endogenous steroid metabolite derived from progesterone
• Studied for GABA-A receptor modulation
• Research focus on inhibitory neurotransmission pathways
• Involved in neurosteroid signaling studies
• Suitable for neuroscience and neurochemical research
• ≥98% purity (research grade standard)
• Strictly for laboratory use only

Chemical & Molecular Information

• Compound Name: Pregnanolone
• CAS Number: 128-20-1
• PubChem CID: 91451
• Molecular Formula: C21H34O2
• Molecular Weight: 318.50 g/mol
• Classification: Neurosteroid
• IUPAC Name: 1-[(3R,5R,8R,9S,10S,13S,14S,17S)-…ethanone]
• Synonyms: Pregnanolone, Eltanolone
• Source Database: PubChem (NCBI)
• Usage: Laboratory and research use only

Mechanism of Action (Research Perspective)

Pregnanolone is primarily studied for its interaction with gamma-aminobutyric acid type A (GABA-A) receptors in the central nervous system. Rather than directly activating receptors, it acts as a positive allosteric modulator, influencing receptor sensitivity to endogenous GABA.

Key research-observed mechanisms include:

• Positive allosteric modulation of GABA-A receptors
• Enhancement of inhibitory neurotransmission signaling
• Regulation of synaptic excitability in experimental models
• Interaction with steroid-binding sites on receptor complexes
• Influence on neuroendocrine signaling pathways

These effects are widely studied in laboratory models to understand inhibitory signaling and neurosteroid function.

Research Applications

Pregnanolone is commonly used in scientific research for:

• GABAergic signaling pathway studies
• Neurosteroid receptor modulation research
• Inhibitory neurotransmission analysis
• Synaptic activity and excitability studies
• Neuroendocrine regulation research
• Steroid metabolism and neurochemistry studies

Scientific Summary

Research indicates that Pregnanolone plays an important modulatory role in the central nervous system by influencing GABA-A receptor activity. As a neurosteroid, it contributes to the regulation of inhibitory neurotransmission and is widely used in experimental models investigating brain signaling and steroid-based modulation of neuronal activity.

Why Choose PureRawz Pregnanolone?

PureRawz provides high-quality research compounds manufactured under strict laboratory standards to ensure purity, consistency, and reliability. Each batch is verified through quality control processes suitable for scientific research.

Through nexacore.pk, researchers in Pakistan can access premium neurosteroids, peptides, SARMs, and other advanced research compounds designed for laboratory use.

Important Disclaimer

Pregnanolone is supplied strictly for laboratory and research purposes only. It is not approved for human consumption, medical treatment, or veterinary use. All research must be conducted in compliance with applicable institutional and regulatory guidelines.