Follistatin (FST) Recombinant Protein – PureRawz

Follistatin is a naturally occurring regulatory protein encoded by the FST gene and associated with the transforming growth factor-beta (TGF-β) superfamily. It is widely studied in molecular biology for its ability to bind and regulate key signaling ligands such as activin and myostatin.

In controlled laboratory environments, Follistatin is used to investigate how ligand-binding proteins influence cellular communication, receptor activity, and downstream signaling pathways. Researchers use this protein to better understand mechanisms related to growth factor regulation and extracellular signaling balance.

For researchers in Pakistan, nexacore.pk provides access to premium research compounds including peptides, SARMs, and advanced protein-based materials such as Follistatin by PureRawz, ensuring reliable quality and research-grade consistency.

Key Features

• High-purity recombinant Follistatin (FST) protein
• Research-grade peptide/protein complex
• Studied for activin and myostatin binding activity
• Supports cellular signaling and molecular biology research
• Suitable for protein interaction and pathway studies
• ≥98% purity standard (where applicable)
• Intended strictly for laboratory research use
• Quality-tested with Certificate of Analysis

Chemical & Molecular Information

• Gene Origin: FST (Follistatin gene product)
• Protein Type: Glycoprotein / regulatory binding protein
• Molecular Weight: ~37–40 kDa (isoform dependent)
• Amino Acid Length: ~344 amino acids
• Classification: TGF-β superfamily regulatory protein
• Structure: Cysteine-rich domain protein
• Purity: ≥98% (research grade standard)
• Usage: Laboratory and research use only

Mechanism of Action (Research Perspective)

Follistatin functions primarily through high-affinity binding interactions with signaling ligands such as activin and myostatin. By binding to these molecules, it prevents their interaction with activin receptors (ActRIIA and ActRIIB), thereby influencing downstream cellular signaling.

Key research observations include:

• Formation of stable protein–ligand complexes
• Inhibition of ligand-receptor activation pathways
• Indirect modulation of SMAD signaling cascades
• Regulation of extracellular signaling environments
• Influence on transcriptional activity through upstream ligand control

These properties make Follistatin an important protein for studying growth factor regulation and cellular communication networks.

Research Applications

Follistatin is widely used in laboratory research for:

• Growth factor signaling studies
• Myostatin and activin pathway research
• Cellular proliferation and differentiation studies
• Protein–ligand interaction analysis
• SMAD signaling pathway investigations
• Extracellular matrix and signaling regulation research

Why Choose PureRawz Follistatin?

PureRawz provides high-quality research peptides and proteins designed for scientific accuracy, purity, and consistency. Each batch is produced under strict quality control standards and verified for research reliability.

Through nexacore.pk, researchers in Pakistan can access authentic PureRawz products, including peptides, SARMs, and advanced biological research compounds designed for laboratory use.

Storage Instructions

• Store in a cool, dry environment
• Avoid direct sunlight and heat exposure
• Keep sealed to prevent contamination
• Follow standard laboratory handling protocols

Important Disclaimer

Follistatin (FST) is supplied strictly for laboratory and research purposes only. It is not approved for human consumption, veterinary use, or medical applications of any kind. All research must comply with applicable institutional and regulatory guidelines.